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49’s is a twice daily draw that takes place at lunchtime (12:49) and teatime (17:49) everyday. Times may vary so please check with your bookmaker daily. Six numbers plus a bonus number known as the “Booster” are drawn from balls marked 1-49. You can play either the 6 or 7 number draw (which includes the Booster ball to increase your chances of winning).
You can bet on 1 to 6 numbers from the 49 in each draw. Some bookmakers bet types may vary so please check with your local bookmaker.
The 49’s rules are just a guide, so you need to check the rules of the bookmaker that you place your bet with as they might be different.
Source : https://www.49s.co.uk/49s/how-to-play